Histone deacetylase inhibitors

The Synergistic Combination of the Farnesyl Transferase Inhibitor Lonafarnib and Paclitaxel Enhances Tubulin Acetylation and Requires a Functional Tubulin Deacetylase

Cancer / Mitosis / Cell line / Humans / Low Dose / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect

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HDAC Inhibitors Correct Frataxin Deficiency in a Friedreich Ataxia Mouse Model

Enzyme Inhibitors / Gene expression / Multidisciplinary / Cerebellum / Mice / Animals / Histone Modification / PLoS one / Chromatin / Introns / Histones / Mouse Model / Microarray Analysis / Myocardium / Chromatin Immunoprecipitation / Western blot / Acetylation / Neurodegenerative Disease / Histone deacetylase inhibitor / Nervous System / Autosomal Recessive / Acute Toxicity / Cardiac Disease / Friedreich Ataxia / Gene expression profiling / Histone deacetylase inhibitors / Iron binding proteins / Animals / Histone Modification / PLoS one / Chromatin / Introns / Histones / Mouse Model / Microarray Analysis / Myocardium / Chromatin Immunoprecipitation / Western blot / Acetylation / Neurodegenerative Disease / Histone deacetylase inhibitor / Nervous System / Autosomal Recessive / Acute Toxicity / Cardiac Disease / Friedreich Ataxia / Gene expression profiling / Histone deacetylase inhibitors / Iron binding proteins

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Histone Deacetylase Inhibitors Decrease DNA Methyltransferase-3B Messenger RNA Stability and Down-regulate De novo DNA Methyltransferase Activity in Human Endometrial Cells

Molecular Biology / Cancer / Protein synthesis / Endometrial Cancer / Humans / Female / HIstone Deacetylase / DNA methylation / mRNA stability / Western blot / Protein Expression / Histone deacetylase inhibitor / Hydroxamic Acids / Histone Acetylation / Anticancer Drug / Histone deacetylase inhibitors / Down-Regulation / Female / HIstone Deacetylase / DNA methylation / mRNA stability / Western blot / Protein Expression / Histone deacetylase inhibitor / Hydroxamic Acids / Histone Acetylation / Anticancer Drug / Histone deacetylase inhibitors / Down-Regulation

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Epigenetic Regulation of Lentiviral Transgene Vectors in a Large Animal Model

Pharmacology / Genetics / Technology / HIV / Biological Sciences / Molecular / Animals / DNA methylation / CpG islands / Transgenic Animals / Animal Model / Swine / Histone deacetylase inhibitor / Human Disease / Human Fibroblasts / Transgene Expression / Hydroxamic Acids / Molecular Targeted Therapy / Gene Transfer / Histone deacetylase inhibitors / Histone deacetylases / Molecular / Animals / DNA methylation / CpG islands / Transgenic Animals / Animal Model / Swine / Histone deacetylase inhibitor / Human Disease / Human Fibroblasts / Transgene Expression / Hydroxamic Acids / Molecular Targeted Therapy / Gene Transfer / Histone deacetylase inhibitors / Histone deacetylases

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Inhibition of Histone Deacetylase Activity in Human Endometrial Stromal Cells Promotes Extracellular Matrix Remodelling and Limits Embryo Invasion

Gene expression / Multidisciplinary / Extracellular Matrix / Pregnancy / Humans / Female / HIstone Deacetylase / Young Adult / PLoS one / Enzyme / Adult / Stromal Cells / Embryos / Hydroxamic Acids / Endometrium / Histone Acetylation / Histone deacetylase inhibitors / Matrix Metalloproteinase / Down-Regulation / Female / HIstone Deacetylase / Young Adult / PLoS one / Enzyme / Adult / Stromal Cells / Embryos / Hydroxamic Acids / Endometrium / Histone Acetylation / Histone deacetylase inhibitors / Matrix Metalloproteinase / Down-Regulation

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Histone Deacetylase Inhibitors Decrease DNA Methyltransferase-3B Messenger RNA Stability and Down-regulate De novo DNA Methyltransferase Activity in Human Endometrial Cells

Molecular Biology / Cancer / Protein synthesis / Endometrial Cancer / Humans / Female / HIstone Deacetylase / DNA methylation / mRNA stability / Western blot / Protein Expression / Histone deacetylase inhibitor / Hydroxamic Acids / Histone Acetylation / Anticancer Drug / Histone deacetylase inhibitors / Down-Regulation / Female / HIstone Deacetylase / DNA methylation / mRNA stability / Western blot / Protein Expression / Histone deacetylase inhibitor / Hydroxamic Acids / Histone Acetylation / Anticancer Drug / Histone deacetylase inhibitors / Down-Regulation

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The Novel Deacetylase Inhibitor AR-42 Demonstrates Pre-Clinical Activity in B-Cell Malignancies In Vitro and In Vivo

Apoptosis / Multidisciplinary / Cell line / Humans / Chronic Lymphocytic Leukemia / PLoS one / Mouse Model / Time Dependent / Stromal Cells / MANTLE CELL LYMPHOMA / Acute Lymphoblastic Leukemia / Histone deacetylase inhibitors / PLoS one / Mouse Model / Time Dependent / Stromal Cells / MANTLE CELL LYMPHOMA / Acute Lymphoblastic Leukemia / Histone deacetylase inhibitors

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The Synergistic Combination of the Farnesyl Transferase Inhibitor Lonafarnib and Paclitaxel Enhances Tubulin Acetylation and Requires a Functional Tubulin Deacetylase

Cancer / Mitosis / Cell line / Humans / Low Dose / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect

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The Novel Deacetylase Inhibitor AR-42 Demonstrates Pre-Clinical Activity in B-Cell Malignancies In Vitro and In Vivo

Apoptosis / Multidisciplinary / Cell line / Humans / Chronic Lymphocytic Leukemia / PLoS one / Mouse Model / Time Dependent / Stromal Cells / MANTLE CELL LYMPHOMA / Acute Lymphoblastic Leukemia / Histone deacetylase inhibitors / PLoS one / Mouse Model / Time Dependent / Stromal Cells / MANTLE CELL LYMPHOMA / Acute Lymphoblastic Leukemia / Histone deacetylase inhibitors

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A histone deacetylase inhibitor potentiates retinoid receptor action in embryonal carcinoma cells

Kinetics / Cell Cycle / Chromatin Biology / Enzyme Inhibitors / Epigenetics / Transcription Factors / Apoptosis / Multidisciplinary / Cell Differentiation / Chromatin Remodeling and Epigenetics / Mice / Animals / HIstone Deacetylase / Neurons / Neuronal Differentiation / Time Factors / Retinoic Acid / Histone deacetylase inhibitor / Tretinoin / Transfection / Recombinant Proteins / Hydroxamic Acids / Histone Acetylation / retinoid X receptor / Dimerization / Histone deacetylase inhibitors / Retinoic Acid Receptor / Transcription Factors / Apoptosis / Multidisciplinary / Cell Differentiation / Chromatin Remodeling and Epigenetics / Mice / Animals / HIstone Deacetylase / Neurons / Neuronal Differentiation / Time Factors / Retinoic Acid / Histone deacetylase inhibitor / Tretinoin / Transfection / Recombinant Proteins / Hydroxamic Acids / Histone Acetylation / retinoid X receptor / Dimerization / Histone deacetylase inhibitors / Retinoic Acid Receptor

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The Synergistic Combination of the Farnesyl Transferase Inhibitor Lonafarnib and Paclitaxel Enhances Tubulin Acetylation and Requires a Functional Tubulin Deacetylase

Cancer / Mitosis / Cell line / Humans / Low Dose / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect / Mice / Animals / HIstone Deacetylase / Cell Death / Paclitaxel / Microtubules / Acetylation / Pyridines / Tubulin / Histone deacetylase inhibitors / Histone deacetylases / Piperidines / Synergistic effect

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Histone deacetylase 3 represses HTLV-1 tax transcription

Genetics / Oncology / Gene regulation / Molecular Medicine / Cancer / Cell Cycle / Enzyme Inhibitors / Apoptosis / Humans / Mutation / Virus / Cell / Gene / Histones / Chromatin Immunoprecipitation / Acetylation / Hydroxamic Acids / Gene Expression Regulation / Histone deacetylase inhibitors / Histone deacetylases / Cell Cycle / Enzyme Inhibitors / Apoptosis / Humans / Mutation / Virus / Cell / Gene / Histones / Chromatin Immunoprecipitation / Acetylation / Hydroxamic Acids / Gene Expression Regulation / Histone deacetylase inhibitors / Histone deacetylases

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Epigenetic regulation of vascular endothelial growth factor a dynamic expression in transitional cell carcinoma

Western blotting / Epigenomics / Humans / DNA methylation / Chromatin Immunoprecipitation / MOLECULAR CARCİNOGENESİS / Cell Proliferation / DNA binding proteins / Histone deacetylase inhibitors / MOLECULAR CARCİNOGENESİS / Cell Proliferation / DNA binding proteins / Histone deacetylase inhibitors

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Reticulon RTN1-C CT Peptide: A Potential Nuclease and Inhibitor of Histone Deacetylase Enzymes

Biochemistry / DNA / Humans / Circular Dichroism / Animals / HIstone Deacetylase / Endoplasmic Reticulum / Peptides / Plasmids / Enzyme / Metals / Rats / Acetylation / Amino Acid Sequence / Biochemistry and cell biology / Histone deacetylase inhibitors / Histone deacetylases / Molecular Sequence Data / HIstone Deacetylase / Endoplasmic Reticulum / Peptides / Plasmids / Enzyme / Metals / Rats / Acetylation / Amino Acid Sequence / Biochemistry and cell biology / Histone deacetylase inhibitors / Histone deacetylases / Molecular Sequence Data

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Reticulon RTN1-CCT Peptide: A Potential Nuclease and Inhibitor of Histone Deacetylase Enzymes

Biochemistry / DNA / Humans / Circular Dichroism / Animals / HIstone Deacetylase / Endoplasmic Reticulum / Peptides / Plasmids / Enzyme / Metals / Rats / Acetylation / Amino Acid Sequence / Biochemistry and cell biology / Histone deacetylase inhibitors / Histone deacetylases / Molecular Sequence Data / HIstone Deacetylase / Endoplasmic Reticulum / Peptides / Plasmids / Enzyme / Metals / Rats / Acetylation / Amino Acid Sequence / Biochemistry and cell biology / Histone deacetylase inhibitors / Histone deacetylases / Molecular Sequence Data

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